2-Oxo-1-oxa-8-azaspiro[4.5]decane-8-carboxylic acid 1,1-dimethylethyl ester
tert-butyl 2-oxo-1-oxa-8-azaspiro[4.5]decane-8-carboxylate
CAS: 301226-27-7
Molecular Formula: C13H21NO4
2-Oxo-1-oxa-8-azaspiro[4.5]decane-8-carboxylic acid 1,1-dimethylethyl ester - Names and Identifiers
2-Oxo-1-oxa-8-azaspiro[4.5]decane-8-carboxylic acid 1,1-dimethylethyl ester - Physico-chemical Properties
| Molecular Formula | C13H21NO4 |
| Molar Mass | 255.31 |
| Density | 1.16±0.1 g/cm3 (20 ºC 760 Torr) |
| Boling Point | 399.6±35.0 °C(Predicted) |
| Flash Point | 195.5°C |
| Vapor Presure | 1.36E-06mmHg at 25°C |
| pKa | -0.84±0.20(Predicted) |
| Storage Condition | Sealed in dry,Room Temperature |
| Sensitive | Irritant |
| Refractive Index | 1.51 |
| MDL | MFCD11100196 |
2-Oxo-1-oxa-8-azaspiro[4.5]decane-8-carboxylic acid 1,1-dimethylethyl ester - Risk and Safety
| Hazard Class | IRRITANT |
2-Oxo-1-oxa-8-azaspiro[4.5]decane-8-carboxylic acid 1,1-dimethylethyl ester - Introduction
tert-butyl 2-oxo-1-oxa-8-azaspiro[4.5]decane-8-carboxylate is an organic compound with the chemical formula C16H27NO4 and a molecular weight of 297.39g/mol. It is a white crystalline solid commonly used in organic synthesis.
The main use of this compound is as an intermediate in organic synthesis. It can be used as a starting material for the synthesis of other complex organic molecules, such as drugs, fragrances and cosmetics. Due to its structural stability and reactivity, it can undergo a variety of reactions, such as nucleophilic addition, acylation and reduction.
The method for preparing tert-butyl 2-oxo-1-oxa-8-azaspiro[4.5]decane-8-carboxylate is as follows: First, 2-oxo-1-oxo-8-n-boc-tetrahydropyrrolidine Dione and tert-butanol are reacted under acidic conditions, the tert-butyl 2-oxo-1-oxa-8-azaspiro[4.5]decane-8-carboxylate was obtained. After completion of the reaction, the product is purified by crystallization or extraction.
For safety information, the compound should follow general laboratory safety practices. It has low toxicity, but should still avoid contact with skin and eyes. Wear appropriate protective equipment such as gloves and goggles during operation. If accidental contact or ingestion occurs, seek medical attention immediately.
The main use of this compound is as an intermediate in organic synthesis. It can be used as a starting material for the synthesis of other complex organic molecules, such as drugs, fragrances and cosmetics. Due to its structural stability and reactivity, it can undergo a variety of reactions, such as nucleophilic addition, acylation and reduction.
The method for preparing tert-butyl 2-oxo-1-oxa-8-azaspiro[4.5]decane-8-carboxylate is as follows: First, 2-oxo-1-oxo-8-n-boc-tetrahydropyrrolidine Dione and tert-butanol are reacted under acidic conditions, the tert-butyl 2-oxo-1-oxa-8-azaspiro[4.5]decane-8-carboxylate was obtained. After completion of the reaction, the product is purified by crystallization or extraction.
For safety information, the compound should follow general laboratory safety practices. It has low toxicity, but should still avoid contact with skin and eyes. Wear appropriate protective equipment such as gloves and goggles during operation. If accidental contact or ingestion occurs, seek medical attention immediately.
Last Update：2024-04-09 21:04:16
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